DAWA-CPM 60ML (CHLORPHENIRAMINE)

Chlorpheniramine maleate is used for the symptomatic relief of allergic conditions including urticaria and angioedema
(rhinitis and conjunctivitis), and in pruritic skin disorders.
It is a common ingredient of compound preparations for symptomatic treatment of coughs and the common cold.
Chlorpheniramine may be administered intravenously as an adjunct in the emergency treatment of anaphylactic shock
Dosage and Administration:
Adults: Two 5ml spoonfuls every 4 – 6 hours
Children: 1 – 2 years: Half 5ml spoonful twice daily
Children: 2 – 5 years: Half 5ml spoonful every 4 – 6 hours
Children: 6 – 12 years: One 5ml spoonful every 4 – 6 hours
Adverse Effects:
chlorpheniramine maleate causes CNS depression, with effects varying from slight drowsiness to deep sleep, and including lassitude,
dizziness, and incoordination (although paradoxical stimulation may occasionally occur, especially at high doses and in children or the
elderly). These sedative effects, when they occur, may diminish after a few days of treatment.
Other adverse effects that are more common with chlorpheniramine maleate include headache, psychomotor impairment, and
antimuscarinic effects such as dry mouth, thickened respiratory-tract secretions, blurred vision, urinary difficulty or retention, constipation,
and increased gastric reflux.Occasional gastrointestinal adverse effects of chlorpheniramine maleate include nausea, vomiting, diarrhoea,
or epigastric pain. Blood disorders, including agranulocytosis, leucopenia, haemolytic anaemia, and thrombocytopenia, although rare,
have been reported.
Other adverse effects that have been reported include convulsions, sweating, myalgia, paraesthesias, extrapyramidal effects, tremor,
sleep disturbances, depression, confusion, tinnitus, hypotension, and hair loss. Allergies (in the form of rash, urticaria and angio-oedema)